CRISPR is a cutting edge gene-editing technology that can target and remove strands of DNA, like a pair of molecular scissors. But the technology isn’t without its shortcomings. This first-generation of CRISPR tech lacks the precision and efficiency to treat certain genetic disorders. However, two American scientists have developed a new Second-Generation CRISPR technology called “base-editing”, which can change DNA structure without actually cutting it.
Prof. Merlin Crossley, Deputy Vice-Chancellor and Professor of Molecular Biology at UNSW joined us to tell us more.